HUMAN HEALTH

CENTRAL NERVOUS SYSTEM INFECTIONS

BioeXsen Meningitis/Encephalitis RT-qPCR MX-17 Panel

Infectious neurological disorder symptoms (meningitis, encephalitis, myelitis, radiculitis, ventriculitis, cerebritis, cerebral or spinal abscess, cyst, extradural abscess, discitis, granuloma, postinfectious encephalitis/cerebellitis/myelitis or radiculoneuropathy) may not indicate a specific agent and isolation of the agent by conventional methods is difficult.

BioeXsen Meningitis/Encephalitis RT-qPCR MX-17 Panel is a one-step reverse transcription and real-time PCR (RT-qPCR) test intended for the presumptive qualitative detection of the viral, bacterial, and fungal agents given below. The kit allows the achievement of RT-qPCR results in 60 minutes (Run time may vary depending on the instrument).

17 TARGETS - 9 Viral 6 Bacterial 2 Fungal Agents

Cryptococcus gattii/neoformans	Listeria monocytogenes
Neisseria meningitidis	Streptococcus pneumoniae
Haemophilus influenzae	Streptococcus agalactiae
Escherichia coli_K1	Cytomegalovirus
Enterovirus	Human Parechovirus
Varicella Zoster Virus	Herpes simplex virus 1
Herpes simplex virus 2	Human Herpesvirus 6
Human Herpesvirus 7	Human Herpesvirus 8

Sample types: Cerebrospinal fluid (CSF).

Sensitivity: 100.00%

Specificity: 98.04%

Specimen
Type

Sample Transfer Method

Extraction Method

LoD (cp/mL)

Sterile

Transport Tube

Zybio EXM3000 Nucleic Acid Isolation System

Validated equipment and devices

Zybio EXM3000 Nucleic Acid Isolation System (Model No: EXM3000) for CSF samples.

CFX96 Touch™/CFX96™ Dx/CFX Opus 96™/CFX Opus 96™ Dx (Bio-Rad) and Magnetic Induction Cycler (Mic) (Bio Molecular System - BMS) Real-Time PCR detection systems equipped with the FAM, HEX, ROX, and CY5 detection channels.

Product	Product Size	Catalog No
Meningitis/Encephalitis RT-qPCR MX-17S Panel	25 Tests	BX-ME-MX17S-25
Meningitis/Encephalitis RT-qPCR MX-17S Panel	100 Tests	BX-ME-MX17S-100

Meningitis/Encephalitis RT-qPCR MX-17T Panel	25 Tests	BX-ME-MX17T-25
Meningitis/Encephalitis RT-qPCR MX-17T Panel	100 Tests	BX-ME-MX17T-100